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Erythrocyte Morphology on Peripheral SmearAka: Erythrocyte Morphology, Microcyte, Spherocyte, Elliptocyte, Schistocyte, Acanthocyte, Spur Cell, Dacryocyte, Howell-Jolly, Target Cell, Basophilic Stippling, Sideroblast, Cabot's Ring Bodies, Red Blood Cell Morphology, Macrocyte
- See Also
- Red Blood Cell
- Peripheral Smear
- Bone Marrow Exam
- Background
- Variants below as seen on Peripheral Smear
- RBC Evaluation parameters
- RBC Color
- RBC Size
- RBC Shape
- RBC Contents
- Macrocytes
- See Macrocytic Anemia
- Reticulocytosis
- Liver disease
- Hypochromic microcytes: Defective Hemoglobin synthesis
- See Microcytic Anemia
- Iron Deficiency Anemia
- Thalassemia
- Sickle Cell Anemia
- Hemoglobinopathy
- Spherocytes
- Hereditary spherocytosis
- Autoimmune Hemolytic Anemia
- Acute Alcoholism
- Hemoglobin C Disease
- Following severe Burn injury
- Hemolytic transfusion reactions
- Severe Hypophosphatemia
- Acute Oxidant Injury: Hexose Monophosphate Shunt Defect
- Clostridium Welchii Septicemia
- Elliptocytes (Oval Cells)
- Megaloblastic Anemia
- Myelofibrosis
- Refractory normoblastic Anemia
- Hereditary elliptocytosis
- Thalassemia
- Schistocytes (Fragmented Red Blood Cells)
- Microangiopathic Hemolytic Anemia
- Disseminated Intravascular Coagulation (DIC)
- Thrombotic Thrombocytopenic Purpura (TTP)
- Hemolytic Uremic Syndrome (HUS)
- Giant Hemangioma
- Metastatic Carcinoma
- Malignant Hypertension
- Eclampsia (Toxemia of Pregnancy)
- Vasculitis
- Macroangiopathic Hemolytic Anemia
- Prosthetic heart valve
- Dacryocytes (tear drop RBC)
- Extramedullary hemopoiesis
- Myelophthisic Anemia
- Severe Hemolytic Anemia
- Erythroleukemia
- Acanthocytes (Spur cells)
- Abetalipoproteinemia
- Cirrhosis
- Hepatic necrosis
- Pyruvate kinase deficiency
- Uremia
- Infantile pyknocytosis
- Howell-Jolly Bodies
- Postsplenectomy
- Megaloblastic Anemia
- Basophilic stippling (aggregated ribosomes)
- Lead Poisoning
- Arsenic poisoning
- Thalassemia
- Sideroblastic Anemia
- Hemolytic Anemia
- Severe Anemia
- Unstable Hemoglobin
- Pyrimidine 5'-Nucleotidase Deficiency
- Heinz Body (Aggregates of denatured Hemoglobin)
- Oxidative Hemolytic Anemia (G6PD Deficiency)
- Target Cells
- Thalassemia
- Hemoglobin C
- Hemoglobin S (Sickle Cell Anemia)
- Liver Disease
- Sideroblasts
- See Sideroblastic Anemia
- Nucleated RBCs
- Iron laden mitochondria
- Cabot's Ring Bodies (Nuclear remnants)
- Lead Toxicity
- Pernicious Anemia
- Hemolytic Anemia
- Other findings on RBC exam
- Malaria
- Bartonella parasites
- References
- Ravel (1995) Clinical Laboratory Medicine, p. 14-16
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| Definition (MSH) | Erythrocytes with protoplasmic projections giving the cell a thorny appearance. |
| Definition (NCI) | Erythrocytes with protoplasmic projections giving the cell a thorny appearance. (MeSH) |
| Concepts | Cell (T025)
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| English | Acanthocyte, Acanthocytes, Acanthrocyte, Crenated cell, Spiny prickle cell, Spur cell |
| Spanish | acantocito |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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| Definition (MSH) | Small, abnormal spherical red blood cells with more than the normal amount of hemoglobin. |
| Definition (NCI) | Small, abnormal spherical red blood cells with more than the normal amount of hemoglobin. (MeSH) |
| Concepts | Cell (T025)
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| English | Spherocyte, Spherocytes |
| Spanish | esferocito |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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Dacryocyte (cell) (C0221266)
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| Concepts | Cell or Molecular Dysfunction (T049)
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| English | Dacrocytosis, Dacryocyte, Dacryocytes, Tear drop cell, TEAR DROP CELLS, Teardrop cell, Teardrop cells |
| Spanish | células lagrimales, celulas lagrimales, dacriocito, dacriocitosis, lacrimocitos |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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Elliptocyte (cell) (C0221280)
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| Concepts | Cell (T025)
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| English | Elliptocyte, ELLIPTOCYTES, Ovalocyte, OVALOCYTES, Pencil cell, Pencil cells |
| Spanish | célula en lápiz, celula en lapiz, eliptocito, ovalocito |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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| Concepts | Cell (T025)
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| English | Fragmented cell, Helmet cell, Helmet cells, Schistocyte, SCHISTOCYTES, Schistocytosis |
| Spanish | célula en casco, célula fragmentada, celula en casco, celula fragmentada, eritrocitos con forma de yelmo, esquistocito, esquistocitosis |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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Macrocytic erythrocyte (C0333805)
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| Definition (NCI) | An abnormally large red blood cell occurring mainly in anemias (as pernicious anemia), also called megalocyte. Lack of vitamin B12 and folic acid could also cause macrocytes. (NCI) |
| Concepts | Cell (T025)
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| English | Macrocyte, Macrocytes, Macrocytic erythrocyte, Macrocytic Red Blood Cell |
| Spanish | eritrocito macrocÃtico, eritrocito macrocitico, macrocito |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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Microcytic erythrocyte (cell) (C0369668)
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| Concepts | Cell (T025)
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| English | Microcyte, Microcytes, Microcytic erythrocyte, Microcytic Red Blood Cell |
| Spanish | eritrocito microcÃtico, eritrocito microcitico, microcito |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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