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Basophil CountAka: Basophil, Basophilia
- See Also
- Complete Blood Count
- Characteristics
- Function: Allergic Response
- Similar mechanism of action to mast cells
- Related to delayed hypersensitivity response
- Triggered by IgE binding to antigen
- Releases inflammatory mediators
- Preformed mediators (e.g. Histamine, Bradykinin)
- New Mediators (e.g. Prostaglandins, Leukotrienes)
- Chemotactic factors attract Neutrophil, Eosinophil
- Morphology on Blood Smear
- Granulocyte cytoplasm stains darkly with Wright Stain
- Two lobed nucleus
- Normal Levels
- Range: 0.4-1.0% (Least common Leukocyte)
- Increased Basophils (Basophilia)
- Viral infections (e.g. Varicella)
- Hodgkin's Lymphoma
- Hemolytic Anemia
- Following splenectomy
- Myeloproliferative disease
- Chronic Myelogenous Leukemia
- Polycythemia Vera
- Myelofibrosis
- Inflammatory processes
- Inflammatory Bowel Disease
- Chronic dermatitis
- Asthma
- Chronic Sinusitis
- Endocrine causes
- Hypothyroidism
- Increased Estrogen
- Decreased Basophils
- Stress
- Hypersensitivity Reaction
- Corticosteroids
- Pregnancy
- Hyperthyroidism
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| Definition (MSH) | Granular leukocytes characterized by a relatively pale-staining, lobate nucleus and cytoplasm containing coarse dark-staining granules of variable size and stainable by basic dyes. |
| Definition (CSP) | granular leukocytes characterized by a relatively pale-staining, lobate nucleus and cytoplasm containing coarse dark-staining granules of variable size and stainable by basic dyes; contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. |
| Definition (NCI) | A type of granular leukocyte with granules that are easily stained by basic stains. |
| Concepts | Cell (T025)
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| English | Basophil, basophilic granulocyte, basophilic leukocyte, Basophils |
| Spanish | basófilo, basofilo, granulocito basófilo, granulocito basofilo |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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Basophil count (C0200641)
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| Concepts | Laboratory Procedure (T059)
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| English | Basophil count |
| Spanish | recuento de basófilos, recuento de basofilos |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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| Concepts | Finding (T033)
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| ICD9 | 288.65 |
| English | Basophilia, Basophilic leucocytosis, Basophilic leukocytosis |
| Spanish | basofilia, leucocitosis con basofilia |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
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