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Antithrombin III

Aka: Antithrombin III
  1. Indications
    1. Hypercoagulable state evaluation
  2. Normal
    1. Activity: 80-120% of normal activity
    2. Level: 17-30 mg/dl
  3. Increased
    1. Warfarin (Coumadin)
    2. Post-Myocardial Infarction
  4. Decreased
    1. Hereditary Antithrombin III deficiency
    2. Disseminated Intravascular Coagulation
    3. Pulmonary Embolus
    4. Cirrhosis
    5. Thrombolysis
    6. Chronic liver failure
    7. Post-surgery
    8. Nephrotic Syndrome
    9. Sepsis
    10. Medications
      1. Intravenous Heparin use longer than 3 days
      2. Oral Contraceptive Use

Antithrombin III (C0003438)

Definition (MSH) A plasma alpha 2 glycoprotein that accounts for the major antithrombin activity of normal plasma and also inhibits several other enzymes. It is a member of the serpin superfamily.
Definition (CSP) blood glycoprotein which inhibits thrombin and other blood coagulation factors; important to maintenance of normal blood fluidity.
Concepts Amino Acid, Peptide, or Protein (T116) , Pharmacologic Substance (T121)
MSH D000990
SnomedCT 259743002, 34086003, 46553007, 395241004, 5485005, 109001008, 386959004
English Antithrombin III, antithrombin III, ANTITHROMBIN III, Antithrombin II (substance), Antithrombin II, Heparin Co Factor I, Heparin Co-Factor I, Cofactor I, Heparin, Heparin Cofactor I, Heparin cofactor I (substance), Antithrombin III product (product), Serpin C1, Antithrombin III [Chemical/Ingredient], Antithrombin, antithrombin iii, factor inhibitors xa, antithrombin, Antithrombin III product, Heparin cofactor I, Antithrombin III (substance), Antithrombin III preparation (product), Antithrombin III preparation, Heparin cofactor I -RETIRED-, Antithrombin II -RETIRED-, Antithrombin III preparation (substance)
Swedish Antitrombin III
Czech antithrombin III
Spanish cofactor de la heparina I, antitrombina II (sustancia), antitrombina II, Antithrombin III product, antithrombin III, antithrombin III (producto), antitrombina II - RETIRADO - (concepto no activo), antitrombina II - RETIRADO -, antitrombina III (sustancia), antitrombina III, cofactor I de heparina - RETIRADO - (concepto no activo), cofactor I de heparina - RETIRADO -, preparado con antitrombina III (producto), preparado con antitrombina III, preparado de antitrombina III (producto), preparado de antitrombina III (sustancia), preparado de antitrombina III, Antitrombina III, Cofactor I de Heparina
Finnish Antitrombiini III
Italian Antitrombina II, Inibitore del fattore Xa, Eparina cofattore I, Antitrombina III
Russian ANTITROMBIN II, GEPARINOVYI KOFAKTOR, ANTITROMBIN III, АНТИТРОМБИН III, АНТИТРОМБИН II, ГЕПАРИНОВЫЙ КОФАКТОР
Japanese 抗トロンビン2, 抗トロンビン3, ヘパリン補因子I, アンチトロンビンIII, アンチトロンビン2, アンチトロンビンII, アンチトロンビン3
French Inhibiteur du facteur Xa, Antithrombine progressive, Cofacteur-I de l'héparine, Antithrombine III, Antithrombine-III, Protéine antithrombine-III, Co-facteur-I de l'héparine, Serpine C1
Croatian ANTITROMBIN III
Polish Antytrombina III, AT III
German Antithrombin III, Antithrombin II, Heparin-Cofaktor I
Portuguese Antitrombina III, Co-Fator I de Heparina
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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