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Microangiopathic AnemiaAka: Microangiopathic Hemolytic Anemia, Fragmentation Hemolysis, MAHA

See Also
1. Hemolytic Anemia
Mechanism
1. RBCs damaged by injured vessel endothelium
2. Results in Schistocyte formation
Causes
1. Prosthetic Heart Valve
2. Vasculitis
3. Malignant Hypertension
4. Eclampsia
5. Renal graft rejection
6. Giant Hemangioma
7. Scleroderma
8. Thrombotic Thrombocytopenic Purpura (TTP)
9. Hemolytic Uremic Syndrome (HUS)
10. Disseminated Intravascular Coagulation (DIC)
11. March Hemoglobinuria (Marathon runners)
Examination
1. Blood Pressure
Labs
1. Peripheral Smear
  1. Schistocytes
2. Liver Function Tests
3. Renal Function Tests
4. ProTime (PT)
5. Partial Thromboplastin Time (aPTT)
References
1. Udden in Goldman (2000) Cecil Medicine. p. 882-4

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 5/10/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.