Coagulopathy

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Common Clotting Pathway

Pathway
1. Factor Xa
  1. Cofactor: Factor V
  2. Inhibitors: Protein C, Protein S
2. Factor II (Prothrombin) converted to IIa (Thrombin)
  1. Fibrinogen cleaved
    1. Fibrinogen cleaved to Fibrin Monomer
    2. Fibrin Monomer coalesced into Fibrin Polymer
  2. Factor XIII converted to XIIIa
    1. Fibrin polymer cross-linked

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 6/1/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.

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Coagulopathy

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Common Clotting Pathway

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