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Purpura Causes

See Also
1. Purpura
2. Bleeding Disorder
Causes: Platelet Disorders
1. See Thrombocytopenia (Most common)
2. See Platelet Dysfunction
Causes: Coagulation Factor Deficiency
1. Congenital
2. Acquired
  1. Disseminated Intravascular Coagulopathy
  2. Liver disease
  3. Vitamin K Deficiency
  4. Uremia
Causes: Vascular Factors
1. Congenital
  1. Hereditary Hemorrhagic Telangiectasia
    1. Autosomal dominant
    2. Fragile telangiectasias of skin and mucus membranes
  2. Ehlers-Danlos Syndrome (Type IV)
    1. Skin hyperelasticity
    2. Joint hypermobility
    3. Fragile skin and blood vessels
2. Acquired: Infections
  1. Henoch-Schonlein Purpura (HSP)
  2. Meningococcemia
  3. Rickettsial Disease
  4. Measles
  5. Scarlet Fever
  6. Typhoid
3. Acquired: Medications
  1. Atropine
  2. Chloral Hydrate
  3. Long-term Corticosteroids
  4. Iodides
  5. Arsenicals
4. Acquired: Trauma
  1. Violent coughing, Vomiting or strangulation
    1. Petechiae in the head and neck
  2. Factitious Purpura (linear Petechiae)
  3. Religious rituals (e.g. Cupping or coining)
  4. Child Abuse
  5. Psychogenic Purpura (Gardner-Diamond Syndrome)
5. Acquired: Other
  1. Vitamin C Deficiency (Scurvy)
References

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 6/1/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.