Hematology and Oncology Book

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Fibrinolysis

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  1. Pathophysiology
    1. Abnormal Plasminogen-plasmin function
      1. Decreased plasminogen activity
      2. Decreased functional plasminogen levels
      3. Defective release of plasminogen levels
      4. Plasminogen activator inhibitors?
  2. Labs
    1. Very prolonged euglobin or whole blood clot lysis time

Fibrinolysis (C0016017)

Definition (MSH)The natural enzymatic dissolution of FIBRIN.
Definition (CSP)natural enzymatic dissolution of fibrin.
Definition (GO)An ongoing process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, resulting in the removal of small blood clots. [GOC:jl, http://cancerweb.ncl.ac.uk/]
ConceptsPhysiologic Function (T039)
MSHD005342
EnglishFibrinolyses, Fibrinolysis
Spanishfibrinolisis
Parent Conceptsfibrinolytic system (C0814026), Blood coagulation (C0005778), negative regulation of blood coagulation (C1160614), Hematologic function (C0221130)
SourcesAOD, CSP, GO, LCH, MSH, MTH, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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