Hematology and Oncology Book

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Fibrinolysis

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  1. Pathophysiology
    1. Abnormal Plasminogen-plasmin function
      1. Decreased plasminogen activity
      2. Decreased functional plasminogen levels
      3. Defective release of plasminogen levels
      4. Plasminogen activator inhibitors?
  2. Labs
    1. Very prolonged euglobin or whole blood clot lysis time

Fibrinolysis (C0016017)

Definition (MSH)The natural enzymatic dissolution of FIBRIN.
Definition (CSP)natural enzymatic dissolution of fibrin.
Definition (GO)An ongoing process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, resulting in the removal of small blood clots. [GOC:jl, http://cancerweb.ncl.ac.uk/]
ConceptsPhysiologic Function (T039)
EnglishFibrinolyses, Fibrinolysis
Spanishfibrinólisis, fibrinolisis
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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