Hematology and Oncology Book

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Sarcoma

Aka: Sarcoma
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  1. Definition
    1. Cancer arrising in mesenchymal (connective) tissue
    2. Derived from greek word "sar" meaning fleshy
  2. Types
    1. Soft-tissue Sarcomas
      1. Kaposi's Sarcoma
      2. Hepatic angiosarcoma
      3. Rhabdomyosarcoma
        1. Most common soft tissue Sarcoma in children
      4. Leiomyosarcoma
        1. Involves Uterus in adults
        2. Involves Retroperitoneum in children
      5. Liposarcoma
        1. Rare adipose tumor (usually invades locally only)
        2. Involves deep thigh or Retroperitoneum
      6. Fibrosarcoma
        1. Most common soft tissue Sarcoma in age <1 year
        2. Involves deep thigh or Retroperitoneum
    2. Vascular Sarcoma
      1. Angiosarcoma
      2. Hemangioendothelioma
      3. Hemangiopericytoma
    3. Bone tumors
      1. Ewing's Sarcoma
      2. Osteogenic Sarcoma

Sarcoma (C1261473)

Definition (NCI) A malignant mesenchymal neoplasm arising exclusively from the soft tissues. Representative examples include soft tissue sarcoma, extraosseous Ewing sarcoma/peripheral primitive neuroectodermal tumor, and malignant hemangiopericytoma.
Definition (NCI) A malignant mesenchymal neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones.
Definition (MEDLINEPLUS)

Your soft tissues connect, support or surround other tissues. Examples include your muscles, tendons, fat and blood vessels. Soft tissue sarcoma is a cancer of these soft tissues. There are many kinds, based on the type of tissue they started in. Sometimes they spread and can press on nerves and organs, causing problems such as pain or trouble breathing.

No one knows exactly what causes these cancers. They are not common, but you have a higher risk if you have been exposed to certain chemicals, had radiation therapy or have certain genetic diseases.

To diagnose soft tissue sarcomas, doctors must remove and look at a piece of the tumor under a microscope. Treatments include surgery to remove the tumor, radiation therapy, chemotherapy or a combination.

NIH: National Cancer Institute
Definition (NCI) A malignant mesenchymal tumor for which a distinct line of differentiation cannot be determined. This term may be used for small biopsy specimens for which adequate tissue is not present for definitive classification.
Definition (MSH) A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
Definition (CSP) any of a group of tumors usually arising from connective tissue, although the term now includes some of epithelial origin; most are malignant.
Definition (NCI) A cancer of the bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue.
Definition (NCI) A usually aggressive malignant mesenchymal cell tumor most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels. Sarcomas occur in both children and adults. The prognosis depends largely on the degree of differentiation (grade) of the tumor. Representative subtypes are liposarcoma, leiomyosarcoma, osteosarcoma, and chondrosarcoma.
Concepts Neoplastic Process (T191)
MSH D012509
ICD10 M8800/3
SnomedCT 424952003, 424413001, 93765001, 2424003, 189764008, 269469005, 363362006, 269634000
French SARCOME, Tumeur maligne des tissus mous SAI, Sarcome SAI, Sarcomes des tissus mous, Tumeur maligne des tissus mous, Sarcome des tissus mous, Sarcome, Sarcomes
English Sarcoma, Soft Tissue, Sarcomas, Soft Tissue, Soft Tissue Sarcomas, SARCOMA, Malig tumor of soft tissue, Malig tumour of soft tissue, Sarcoma, NOS, Sarcoma of the Soft Tissue and Bone, soft tissue sarcoma, Sarcoma of soft tissue, Sarcoma (disorder), Sarcoma of soft tissue (disorder), [M]Sarcoma NOS, Malignant neop of soft tissue, Sarcoma NOS, Malignant neoplasm of soft tissues, malignant neoplasm of soft tissue, sarcoma of soft tissue, sarcoma (diagnosis), sarcoma, malignant neoplasm of soft tissue (diagnosis), sarcoma of soft tissue (diagnosis), Sarcoma, no ICD-O subtype, malignant soft tissue neoplasm, Malignant soft tissue neoplasm NOS, Soft tissue sarcomas, SOFT TISSUE TUMOR MALIGNANT, [M]Sarcoma NOS (morphologic abnormality), malignant tumor of soft tissue, Sarcoma [Disease/Finding], Sarcoma, malignant soft tissue tumors, sarcomas soft tissue, cancer of the soft tissue, mesenchymal malignant tumor, sarcomas, soft tissue sarcomas, sarcoma soft tissue, Malignant soft tissue neoplasm, Soft tissue tumor, malignant, Mesenchymal tumor, malignant, Malignant mesenchymal tumor, Malignant mesenchymal tumour, Malignant tumor of soft tissue, Malignant tumour of soft tissue, Soft tissue sarcoma, Mesenchymal tumour, malignant, Soft tissue tumour, malignant, Malignant neoplasm of soft tissue, Malignant neoplasm of soft tissue (disorder), Sarcoma, no ICD-O subtype (morphologic abnormality), sarcoma; soft tissue, soft tissue; sarcoma, Malignant tumor of soft tissue (disorder), Sarcomas, Soft Tissue Sarcoma, Connective Tissue Sarcoma, Malignant Neoplasm of Soft Tissue, Malignant Neoplasm of the Soft Tissue, Malignant Soft Tissue Neoplasm, Malignant Soft Tissue Tumor, Malignant Tumor of Soft Tissue, Malignant Tumor of the Soft Tissue, Sarcoma of Soft Tissue and Bone, Sarcoma of Soft Tissue, Sarcoma of the Soft Tissue, Neoplasm malig;soft tissue, malignant neosplasm of the soft tissue
Portuguese SARCOMA, Sarcoma NE, Neoplasia maligna dos tecidos moles NE, Sarcomas dos tecidos moles, Neoplasia maligna dos tecidos moles, Sarcoma, Sarcoma de Tecidos Moles
Spanish SARCOMA, Neoplasia maligna de tejidos blandos NEOM, Sarcoma NEOM, sarcoma de partes blandas (trastorno), sarcoma, sarcoma de partes blandas, sarcoma (trastorno), Sarcoma NOS, Malignant neoplasm NOS, [M]sarcoma, SAI (anomalía morfológica), [M]sarcoma, SAI, morfología: sarcoma, no clasificado como subtipo en CIE - O (anomalía morfológica), tumor mesenquimatoso maligno, tumor mesenquimático maligno, Sarcomas de tejidos blandos, Neoplasia maligna de tejidos blandos, morfología: sarcoma, no clasificado como subtipo en CIE - O, Sarcoma, Sarcoma de Tejidos Blandos, neoplasia maligna de partes blandas, neoplasia maligna de partes blandas (trastorno), neoplasia maligno de partes blandas, neoplasia maligno de partes blandas (trastorno), tumor maligno de partes blandas, tumor maligno de partes blandas (trastorno)
German SARKOM, boesartige Neubildung der Weichteile NNB, Sarkom NNB, Sarkome der Weichteile, boesartige Neubildung der Weichteile, Sarkom, Sarkom, Weichteil-
Italian Sarcomi del tessuto molle, Tumore maligno dei tessuti molli, Tumore maligno dei tessuti molli NAS, Sarcoma NAS, Sarcoma dei tessuti molli, Sarcoma
Dutch wekedelenneoplasma maligne NAO, sarcoom NAO, sarcoom; weke delen, weke delen; sarcoom, sarcoom, wekedelenneoplasma maligne, wekedelensarcomata, Sarcoom, Sarcoom, wekedelen-
Japanese 軟部組織肉腫, 肉腫ＮＯＳ, 軟部組織の悪性新生物ＮＯＳ, 軟部組織の悪性新生物, ﾅﾝﾌﾞｿｼｷﾉｱｸｾｲｼﾝｾｲﾌﾞﾂ, ﾅﾝﾌﾞｿｼｷﾉｱｸｾｲｼﾝｾｲﾌﾞﾂNOS, ﾅﾝﾌﾞｿｼｷﾆｸｼｭ, ﾆｸｼｭ, ﾆｸｼｭNOS, 肉腫-類上皮, 紡錘細胞肉腫, 類上皮肉腫, 肉腫, 紡錘形細胞肉腫, 肉腫-紡錘細胞
Swedish Sarkom
Czech sarkom, Sarkomy měkkých tkání, Maligní novotvar měkké tkáně NOS, Sarkom, Maligní novotvar měkké tkáně, Sarkom NOS
Finnish Sarkooma
Russian SARKOMA, SARKOMA EPITELIOIDNAIA, SARKOMA MIAGKIKH TKANEI, SARKOMA VERETENOKLETOCHNAIA, САРКОМА ЭПИТЕЛИОИДНАЯ, САРКОМА МЯГКИХ ТКАНЕЙ, САРКОМА ВЕРЕТЕНОКЛЕТОЧНАЯ, САРКОМА
Croatian SARKOM
Hungarian Rosszindulatú lágyrész neoplasia, Rosszindulatú lágyrész neoplasia k.m.n., Sarcoma, Lágyszövet sarcomák, Sarcoma k.m.n.
Polish Mięsak
Sources
Derived from the NIH UMLS (Unified Medical Language System)


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