Human Immunodeficiency Virus Book

http://www.fpnotebook.com/

NelfinavirAka: Viracept

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  1. Mechanism
    1. Protease Inhibitor
  2. Efficacy
    1. May be used as first line agent (potent)
    2. Similar to Ritonavir or Indinavir
  3. Dosing
    1. Adult: 750mg PO tid
    2. Pediatrics: 20-30 mg/kg tid
    3. Take with a meal or light snack
  4. Adverse Effects
    1. Well tolerated

Viracept (C0525004)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHD019888
EnglishAgouron Brand of Nelfinavir Mesylate, Roche Brand of Nelfinavir Mesylate, Viracept
SourcesCSP, MSH, NCI, PDQ, RXNORM
Derived from the NIH UMLS (Unified Medical Language System)


Nelfinavir (C0525005)

Definition (MSH)A potent HIV protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children.
Definition (CSP)HIV protease inhibitor.
Definition (NCI)A synthetic antiviral agent. Nelfinavir selectively inhibits human immunodeficiency virus (HIV) protease, thereby preventing cleavage of the gag-pol viral polyprotein and resulting in the release of immature, noninfectious virions. In vivo, this agent exhibits broad tissue distribution compared to related agents. (NCI04)
ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHD019888
EnglishNelfinavir, NELFINAVIR PREPARATION, NFV
Spanishnelfinavir
Parent ConceptsAntiviral Agents (C0003451), Isoquinolines (C0022248), Protease Inhibitor (C0033607), Retroviral protease inhibitor (C1268897), Drug allergen (C1320237), HIV Protease Inhibitors (C0162714)
SourcesCSP, LNC, MSH, NCI, NDFRT, RXNORM, SCTSPA, SNOMEDCT, USPMG, VANDF
Derived from the NIH UMLS (Unified Medical Language System)



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