III. Dosing

  1. Adefovir 120 mg PO qd
  2. Take with L-carnitine 500 mg supplement

IV. Adverse Effects

  1. Nephrotoxicity (30%)
    1. Fanconi Syndrome like condition
  2. Nausea
  3. Diarrhea
  4. Asthenia
  5. Liver Function Test abnormalities

V. Availability

  1. Phone: 1-800-445-3235

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Cost: Medications

adefovir (on 7/20/2016 at Medicaid.Gov Survey of pharmacy drug pricing)
ADEFOVIR DIPIVOXIL 10 MG TAB Generic $24.85 each

Ontology: adefovir (C0050175)

Definition (NCI) A nucleoside reverse transcriptase inhibitor analog of adenosine with activity against hepatitis B virus (HBV), herpes virus, and human immunodeficiency virus (HIV).
Definition (CSP) an adenine analog, antiviral agent; used for treating hepatitis, HIV and African swine fever virus infections.
Concepts Pharmacologic Substance (T121) , Nucleic Acid, Nucleoside, or Nucleotide (T114)
MSH C053001
SnomedCT 412073001, 412072006
LNC LP28549-1, MTHU013860
English 9-(2-phosphonylmethoxyethyl)adenine, 9-PMEA, 9-(2-phosphonomethoxyethyl)adenine, PMEA, Phosphonylmethoxyethyl-a, adefovir, adefovir [Chemical/Ingredient], 9-(2-phophonylmethoxyethyl)adenine, ADEFOVIR, 9-(2-Phosphonylmethoxyethyl)adenine, Adefovir (product), Adefovir (substance), Adefovir
Spanish adefovir (producto), adefovir (sustancia), adefovir

Ontology: Preveon (C0754613)

Concepts Pharmacologic Substance (T121) , Organic Chemical (T109)
MSH C106812
English Preveon