Human Immunodeficiency Virus Book

http://www.fpnotebook.com/

CD4 Cell CountAka: CD4 Count

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  1. Indication
    1. Detecting HIV related Immune Deficiency
    2. Monitoring HIV Disease
    3. Used in combination with Plasma Viral Load Testing
  2. Efficacy
    1. Cell counts vary widely from lab to lab
      1. Use the same lab to follow patients
    2. Diurnal cell count variation (from 50-150 cells/mcl)
    3. May drop to 50% with acute comorbid illness
  3. Normal
    1. Non-HIV patients: 800-1200 cells/mcl
  4. Interpretation
    1. See HIV Course
    2. Each CD4 Count 10% rise decreases progression risk 15%
  5. References
    1. Hughes (1997) Ann Intern Med 126:929
    2. Mellors (1997) Ann Intern Med 126:946
    3. O'Brien (1997) Ann Intern Med 126:939

CD4 Count determination procedure (C0243009)

Definition (MSH)The number of CD4-POSITIVE T-LYMPHOCYTES per unit volume of BLOOD. Determination requires the use of a fluorescence-activated flow cytometer.
ConceptsLaboratory Procedure (T059)
EnglishCD 004 LYMPHOCYTE COUNT, CD4 Cell Count, CD4 Cell Counts, CD4 Count, CD4 Count determination procedure, CD4 Counts, CD4 Lymphocyte Count, CD4 Lymphocyte Counts, CD4+ Cell Count, CD4+ Cell Counts, CD4+ Count, CD4+ Counts, LYMPHOCYTE COUNT CD 004, LYMPHOCYTE COUNT T 004, T4 Lymphocyte Count, T4 Lymphocyte Counts
Parent ConceptsLymphocyte Count measurement (C0200635)
SourcesMSH, MTH
Derived from the NIH UMLS (Unified Medical Language System)



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