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Hyperandrogenism CausesAka: Androgen Excess Causes

Medications related to excessive androgen exposure
1. Anabolic Steroids
2. Danazol (Danocrine)
3. Metoclopramide (Reglan)
4. Methyldopa (Aldomet)
5. Phenothiazines
6. Oral Contraceptives: High Progestin Androgenic Activity
  1. Levonorgestrel (Nordette, Alesse, Triphasil)
  2. Norethindrone (Loestrin, Estrostep, Ortho Novum 1/35)
  3. Norgestrel (e.g. Ovral, Lo-Ovral, Ovrette)
7. Reserpine (Serpasil)
8. Testosterone
Non-tumor related Endogenous Androgen Overproduction
1. Adrenal Causes
  1. Congenital Adrenal Hyperplasia (CAH)
    1. CAH: 21 Hydroxylase deficiency
    2. CAH: 11 Hydroxylase deficiency
  2. Cushing's Syndrome
2. Ovarian Causes
  1. Polycystic Ovary Disease
  2. Hyperthecosis
  3. HAIR-AN Syndrome (related to Insulin Resistance)
Tumor related Endogenous Androgen Overproduction
1. Adrenal tumors
  1. Adrenocortical tumors
  2. Adrenal adenoma
  3. Adrenal carcinoma
2. Ovarian tumors
  1. Arrhenoblastoma
  2. Hilar Cell Ovarian Tumor
  3. Krukenberg Tumor of the ovary
3. Pituitary tumor
  1. Pituitary Adenoma
References
1. Leung (1993) Int J Dermatol 32:1173

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 6/1/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.