Gynecology Book

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Vaginal Contraceptive RingAka: NuvaRing

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  1. Background
    1. Ethylene vinyl ring
      1. Diameter: 2 inch diameter
      2. Thickness: 1/8 inch
    2. Vaginal ring releases hormones at constant rate
      1. Ethinyl Estradiol 15 mcg/day
      2. Etonogestrel 120 mcg/day
  2. Technique: 4 week cycles
    1. Inserted into vagina on or before day 5 of cycle
    2. Ring left in vagina for 3 weeks
    3. Removed for 1 week for withdrawal bleeding
    4. Backup Contraception needed if ring is out for >3 hours
  3. Efficacy
    1. Failure rate: 0.65 pregnancies per 100 woman years
    2. Compliance is greater than 90%
  4. Adverse effects
    1. Overall ring is well tolerated in 96% of women
    2. Foreign body sensation in vagina
      1. White Vaginal Discharge
      2. Vaginitis
    3. Difficult intercourse with ring in place
    4. Ring may be expulsed from vagina
    5. Headache may occur
  5. Benefits
    1. Easy insertion and well tolerated
    2. Less break-through bleeding than Levonorgestrel OCP
      1. Normal withdrawal bleeding is however more common
    3. Avoids first pass through liver
      1. No effect on lipids
      2. Allows for low Estrogen (15 mcg Ethinyl Estradiol)
    4. No effect on Lactation
  6. References
    1. Massai (2000) :
    2. Mulders (2001) :
    3. Roumen (2001) Hum Reprod 16:469

NuvaRing (C1744678)

ConceptsDrug Delivery Device (T203)
MSHC516519
EnglishNuvaRing
SourcesMSH
Derived from the NIH UMLS (Unified Medical Language System)



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