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Failure to Thrive in the Elderly
- Epidemiology: Incidence
- Community adults: >5%
- Nursing home: >25%
- Hosptalized: >50%
- Pathophysiology: Contributing Factors
- Physical function decline: Weakness, falls, ADL decline
- Malnutrition: Weight loss, anorexia, decreased immunity
- Depression
- Cognitive Impairment (Delirium, Dementia)
- Causes
- Medications
- See Medications to Avoid in Older Adults
- See Polypharmacy
- Most common medication culprits
- Psychotropic medications
- Anticholinergic Medications
- Recently added medications
- Consider non-prescription drug use, herbals
- Missed dose and non-compliance
- Medication Overdosage (or with renal insufficiency)
- Acute
- Infection: Pneumonia, UTI, Cellulitis
- CHF exacerbation
- COPD exacerbation
- Diabetes Mellitus
- Elecrolyte disrders
- Acute gastrointestinal bleeeing
- See Medications above
- Subacute
- Anemia
- Cirrhosis
- Chronic Kidney Disease
- Infection
- Diabetes Mellitus
- See Medications above
- Acute
- Cancer
- Dementia
- Endocrine conditions (Thyroid, Parathyroid disease)
- Tuberculosis
- HIV Infection
- Chronic Obstructive Pulmonary Disease
- Cardiomyopathy
- Valvular heart disease
- Chronic Kidney Disease
- Chronic Liver Disease
- Polymyalgia Rheumatica
- Labs
- Complete Blood Count
- Chemistry panel including Renal Functions, electrolytes
- Serum Glucose
- Thyroid Stimulating Hormone
- Urinalysis (consider chronic colonization vs UTI)
- Liver Function Tests
- Erythrocte sedimentation rate or C-Reactive Protein
- Malnutrition Labs
- See Lab Markers of Malnutrition
- Albumin
- Total Cholesterol
- Imaging
- Chest XRay
- Consider Echocardiogram
- Consider anatomic imaging (CT, MRI)
- Consider Pulmonary Function Tests
- Evaluation
- Consider causes above
- Focus on medications
- What medications can be stopped?
- Are medications dosed correctly?
- Interpret doses in light of Renal Function
- Are medication side effects resulting in failure?
- Consider drug interactions
- Management: General
- Treat acute illness
- Optimize chronic disease management
- Manage medications as above (stop those not needed)
- Address Advanced Directives
- See Depression in the Elderly
- Management: Physical Impairment
- Avoid bed rest
- Up in chair for all meals
- Walk twice daily in hallway if able
- Physical Therapy
- Avoid restraints including Foley Catheter
- Bathroom use (up with assistance)
- Management: Malnourishment
- Use oral nutrition supplements
- Sample protocol
- Split one can supplement into four doses
- Take interspersed as snacks
- Take with medications
- Make more palatable by mixing with ice cream
- Prognosis
- Nearly 16% mortality rate
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