Geriatric Medicine Book

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Do-Not-ReuscitateAka: Do-Not-Reuscitate, DNR

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  1. See Also
    1. Advance Care Planning
  2. Definition
    1. Order prohibits Cardiopulmonary Resuscitation (CPR)
    2. Includes Do-Not-Intubate (DNI)
    3. Implementation varies by state (e.g. DNR as outpatient)
    4. Independent of Advance Directive

Daunorubicin (C0011015)

Definition (MSH) A very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of LEUKEMIA and other NEOPLASMS.
Definition (CSP) anthracycline antibiotic produced by Streptomyces coeruleorubidus or Streptomyces peucetius and used as an antineoplastic.
Definition (NCI) An anthracycline antineoplastic antibiotic with therapeutic effects similar to those of doxorubicin. Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated interaction with DNA, thereby inhibiting DNA replication and repair and RNA and protein synthesis.
Definition (NCI) An anticancer drug that belongs to the family of drugs called antitumor antibiotics.
Concepts Organic Chemical (T109) , Pharmacologic Substance (T121)
MSH D003630
English Dauno Rubidomycine, Dauno-Rubidomycine, Daunomycin, Daunorrubicina, Daunorubicin, DAUNORUBICIN PREPARATION, DNM, DNR, DRB, Leukaemomycin C, Rubidomycin, Rubomycin, Rubomycin C
Spanish daunorrubicina
Parent Concepts Anthracycline Antibiotics (C0003234), Anthracyclines (C0282564), Antibiotics, Antineoplastic (C0003236)
Sources CSP , MSH, MTH, NCI, NDFRT, PDQ, RXNORM, SCTSPA, SNOMEDCT, VANDF
Derived from the NIH UMLS (Unified Medical Language System)


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