Gastroenterology Book

http://www.fpnotebook.com/

Hepatitis B Postexposure Prophylaxis in NewbornsAka: Hepatitis B Prophylaxis in Newborns, Postexposure Prophylaxis for Hepatitis B in Newborns

Advertisement

  1. See Also
    1. Postexposure Prophylaxis for Hepatitis B
    2. Hepatitis B
  2. Epidemiology
    1. U.S. Mothers with Chronic Hepatitis B: 19,000 per year
  3. Efficacy
    1. Prophylaxis prevents 90% of perinatal infections
  4. Protocol: Administer HBIG and HepB <12 hours from birth
    1. Indications
      1. Maternal Hepatitis B positive
      2. Maternal Hepatitis B status unknown or positive
    2. Hepatitis B Immunoglobulin (HBIG)
      1. HBIG 0.5 ml within 12 hours of birth
    3. Hepatitis B Vaccine (HepB)
      1. Initial dose within 12 hours of birth
        1. Administer at separate site from HBIG
      2. Repeat Heptavax at exactly 1 and 6 months of age
  5. Monitoring
    1. Check follow-up Hepatitis B labs at age 9-15 months
      1. Hepatitis B Surface Antigen (HBsAg)
      2. Hepatitis B Surface Antibody (xHBs)
  6. References
    1. Euler (2003) Pediatr Infect Dis J 22:123

Navigation Tree