Gastroenterology Book

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Hepatitis EAka: HEV

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  1. See Also
    1. Viral Hepatitis
  2. Epidemiology
    1. Enteric transmission of non-A, non-B Hepatitis
      1. Most common cause in world
    2. Waterborne Illness epidemics in
      1. India
      2. Asia
      3. Africa
      4. Mexico
  3. Course
    1. Self-limited illness
    2. Mortality 10-20% in pregnant women
    3. No associated chronic hepatitis
  4. Pathophysiology
    1. Incubation period: 15-60 days (mean 40 days)
    2. Infectivity: Virus excretion in stool for <14 days
    3. Calicivirus (diameter 32-34 nm))
  5. Signs and Symptoms
    1. See Viral Hepatitis
  6. Differential Diagnosis
    1. See Acute Hepatitis Causes
  7. Management
    1. High calorie diet (better tolerated in morning)
    2. IV Hydration when indicated for severe dehydration
    3. Cholestyramine up to 4g PO qid for severe Pruritus
    4. Avoid drugs with hepatic metabolism

Hepatitis E virus (C0085294)

Definition (MSH)A positive-stranded RNA virus species in the genus HEPEVIRUS, causing enterically-transmitted non-A, non-B hepatitis (HEPATITIS E).
Definition (CSP)positive stranded RNA virus species in an unassigned genus, Hepatitis E like Viruses, causing enterically transmitted non A, non B hepatitis (hepatitis E).
ConceptsVirus (T005)
MSHD016752
EnglishHepatitis E virus, Hepatitis E virus HEV, HEV, HEV - Hepatitis E virus
Spanishvirus de la hepatitis E
Parent ConceptsHepatitis Viruses (C0019186), RNA Viruses (C0035691), Hepevirus (C0446176), Calicivirus (C0206413)
SourcesAOD, CSP, LNC, MSH, MTH, NCBI, NCI, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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