http://www.fpnotebook.com/
Autoimmune Hepatitis
- Epidemiology
- Much more common in women than in men
- Labs
- Transaminases Moderately elevated
- Alanine Aminotransferase (ALT) 150-1000
- Aspartate Aminotransferase (AST) 150-1000
- Cholestasis Labs elevated
- Gamma glutamyl transferase (GGT) elevated
- Alkaline Phosphatase
- Liver Function Tests abnormal
- Albumin depressed
- ProTime prolonged
- Bilirubin elevated
- Diagnosis
- Exclude other liver disease
- Specific Labs (False Negative: 10-20%)
- Antinuclear Antibody (ANA)
- Smooth Muscle Antibody (SMA)
- Anti-LKM Antibody
- Management
- See Prevention of Liver Disease Progression
- Corticosteroids
- Significantly improve survival
- Course
- Severe progressive liver disease is more typical
Hepatitis, Autoimmune (C0241910)
|
|---|
| Definition (MSH) | A chronic self-perpetuating hepatocellular INFLAMMATION of unknown cause, usually with HYPERGAMMAGLOBULINEMIA and serum AUTOANTIBODIES. |
| Concepts | Disease or Syndrome (T047)
|
| English | Autoimmune chronic active hepatitis, Autoimmune hepatitis |
| Spanish | hepatitis activa crónica autoinmune, hepatitis activa cronica autoinmune, hepatitis autoinmune, hepatitis autoinmunitaria |
| Credits | Derived from the NIH UMLS (Unified Medical Language System)
|
Navigation Tree