Gastroenterology Book

Anorectal Disorders

Bowel Disorders

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Pancreatic Disorders

Peptic Ulcer Disease

  • Dyspepsia Red Flags

Splenic Disorders

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Dyspepsia Red Flags

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  1. See Also
    1. Dyspepsia
  2. Red Flags may suggest serious underlying conditions
    1. Gastric Cancer
    2. Complicated Peptic Ulcer Disease
  3. Red Flags in Dyspepsia
    1. Age of onset cut-off
      1. Current age cut-off: age over 45-56 years
      2. Recent literature suggests adjusting based on gender
        1. Age over 35 years in men
        2. Age over 56 years in women
        3. Marmo (2005) Am J Gastroenterol 100:784
    2. Dysphagia
    3. Anorexia or early satiety
    4. Persistent Vomiting
    5. Jaundice
    6. Palpable abdominal mass
    7. Family History of Gastric Cancer
      1. More common in non-caucasian (esp. black patients)
    8. Prior Peptic Ulcer Disease history
    9. Unexplained weight loss
      1. Weight loss more than 3 kg or 6.5 pounds
      2. Weight loss >10% of body weight
    10. Signs of significant Gastrointestinal Bleeding
      1. Anemia
      2. Rectal bleeding or Melena
  4. References
    1. (1998) Gastroenterology 114:579
    2. Meineche-Schmidt (2002) Scand J Gastroenterol 37:999

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