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Intraocular AdrenergicAka: Dipivefrin, Propine
- Indication
- Adjunct to Open Angle Glaucoma therapy
- Mechanism
- Decreases aqueous outflow resistance
- Decreases aqueous production
- Preparations
- Dipivefrin (Propine) 1 drop bid
- Side Effects
- Tachypnea
- Tachycardia
- Hypertension
- Tremor
- Restlessness
- Headache
Dipivefrin (C0058415) | |
|---|---|
| Definition (NCI) | An ester prodrug of epinephrine, with sympathomimetic activity. Due to its lipophilicity, dipivefrin penetrates more easily to the anterior chamber of the eye and is hydrolyzed to epinephrine, when applied locally. Epinephrine, an adrenergic agonist, enhances the outflow of aqueous humor and decreases the production of aqueous humor by vasoconstriction. The overall result is a reduction in intraocular pressure. |
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | C015173 |
| English | adrenaline dipivalate, dipivaloylepinephrine, Dipivalyl adrenaline, Dipivalyl epinephrine, Dipivefrin, DIPIVEFRIN PREPARATION, Dipivefrine, DPE, DPE - Dipivefrin |
| Spanish | dipivalil epinefrina, dipivefrina |
| Parent Concepts | Anti glaucoma agent (C1515995), Epinephrine (C0014563), [OP103] ADRENERGICS, TOPICAL OPHTHALMIC (C0973589), Mydriatics (C0026964), Sympathomimetics (C0039052), Alpha-adrenergic Agonists, Ophthalmic (C1579379) |
| Sources | MSH, MTH, NCI, NDFRT, RXNORM, SCTSPA, SNOMEDCT, USPMG, VANDF Derived from the NIH UMLS (Unified Medical Language System) |
Propine brand of dipivefrin (C0138647) | |
|---|---|
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | C015173 |
| English | Allergan brand of dipivefrin hydrochloride, Diopine, Propine, Propine brand of dipivefrin |
| Sources | MSH, MTH, NCI, RXNORM Derived from the NIH UMLS (Unified Medical Language System) |
