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Benign Premature Thelarche
Aka: Benign Premature Thelarche
- Pathophysiology
- Benign self-limited cause of Precocious Puberty
- Epidemiology
- Onset as early as age 18 months
- Signs
- Early Breast development (not to mature Breast contour)
- No other signs of Puberty
- Normal prepubertal growth rate
- Radiology
- Bone age consistent chronological age
- Ovarian ultrasound normal
- Labs
- Serum Gonadotropin levels normal
- Serum Estradiol normal
- Management
- Reassurance
- Do not biopsy Breast
- Biopsy results in partial Mastectomy
- Further Breast development abnormal post-biopsy
- Course
- Spontaneous resolution