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Benign Premature Thelarche

Pathophysiology
1. Benign self-limited cause of Precocious Puberty
Epidemiology
1. Onset as early as age 18 months
Signs
1. Early breast development (not to mature breast contour)
2. No other signs of Puberty
3. Normal prepubertal growth rate
Radiology
1. Bone age consistent chronological age
2. Ovarian ultrasound normal
Labs
1. Serum Gonadotropin levels normal
2. Serum Estradiol normal
Management
1. Reassurance
2. Do not biopsy breast
  1. Biopsy results in partial Mastectomy
  2. Further breast development abnormal post-biopsy
Course
1. Spontaneous resolution

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This page was written by Scott Moses, MD. This page was last revised before 5/10/08, prior to consistent tracking of revision date. This page was last published on 5/10/2008. Please send comments and questions to the editor. Contact information may be found on the page About the Family Practice Notebook. These pages are best viewed with Microsoft Internet Explorer 6.0.