Endocrinology Book

http://www.fpnotebook.com/

Tall Stature

Aka: Tall Stature
  1. Causes
    1. Constitutional Tall Stature
    2. Familial Tall Stature
    3. Growth Hormone secreting tumors (Gigantism)
    4. Thyrotoxicosis
    5. Marfan Syndrome
    6. Homocystinuria
    7. Cerebral Gigantism (Soto Syndrome)
    8. Beckwith-Wiedemann Syndrome
    9. Congenital Adrenal Hyperplasia (Untreated, pubertal)
    10. Klinefelter Syndrome
    11. Obesity
    12. Precocious Puberty
  2. Evaluation
    1. Assess parental heights!
      1. See Midparental Height
    2. Weight Measurement in Children
    3. Height Measurement in Children
    4. Body Mass Index
    5. Weight for Height Age
    6. See Dysmorphic features in Congenital Dysorders
    7. Upper to Lower Segment Ratio
  3. Labs: Specific
    1. Growth Hormone Level (Gigantism)
    2. Thyroid Stimulating Hormone
    3. Amino acid screen (Homocystinuria)
    4. Chromosome Karyotype (Klinefelter Syndrome)
    5. 17-Hydroxyprogesterone (Congenital Adrenal Hyperplasia)
    6. Glucose (Beckwith-Wiedemann)
    7. Androgen and Estrogen levels (Precocious Puberty)
  4. Imaging
    1. Bone age XRay
  5. Evaluation
    1. Normal exam, bone age and no dysmorphic features
      1. Constitutional Tall Stature
    2. Normal exam without dysmorphic features, but with accelerated bone age
      1. Obesity
      2. Precocious Puberty
      3. Growth Hormone excess
    3. Dysmorphic features and proportionate growth
      1. Beckwith-Wiedemann Syndrome
      2. Weaver Syndrome
    4. Dysmorphic features and dysproportionate growth
      1. Klinefelter Syndrome
      2. Sotos Syndrome
      3. Estrogen deficiency
  6. References
    1. Alpert (1998) Pediatr Rev 19(9):303-5
    2. Cuttler (1987) Pediatrician 14(3):109-20
    3. Leung (1995) Can Fam Physician 41:457-68
    4. Nwosu (2008) Am Fam Physician 78(5): 597-4
    5. Rosenfield (1996) Endocrinol Metab Clin North Am 25:743

Tall stature (C0241240)

Concepts Finding (T033)
SnomedCT 248328003
English STATURE TALL, stature tall, Stature tall, Large stature, Tall stature, Tall stature (finding), stature; tall, tall; stature, tall stature
Dutch grote gestalte, gestalte; groot, groot; gestalte
French Grande taille
German Statur grossgeachsen
Italian Statura alta
Portuguese Estatura alta
Spanish Estatura alta, alta estatura (hallazgo), alta estatura, talla alta
Japanese 高身長, ｺｳｼﾝﾁｮｳ
Czech Vysoký vzrůst
Hungarian Termet magas
Sources
Derived from the NIH UMLS (Unified Medical Language System)


Navigation Tree