Endocrinology Book

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Management

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Diabetes Mellitus Control in Hospital

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  1. See Also
    1. Insulin Sliding Scale
    2. Hourly Subcutaneous Insulin Lispro
    3. Insulin Infusion
  2. Complications: Uncontrolled Blood Glucose
    1. Decreased survival
    2. Increased cardiac or Cerebral Infarction
    3. Increased infectious disease
    4. Post-surgical hyperglycemia correlates to complications
      1. Diabetes Mellitus confers 2 relatve risk complication
      2. BG >200 mg/dl confers >3 relative risk complication
      3. BG >250 mg/dl confers >12 relative risk complication
      4. (2002) :
  3. Targets: Hospitalized Blood Glucose control in ICU
    1. Monitor Blood Glucose every 2-4 hours
    2. ICU goal Blood Glucose: 70-200 mg/dl (ideally <140)
    3. Treat Hypoglycemia with D50 IV
  4. Diagnosis: Evaluate on hospitalization
    1. Check fasting Blood Glucose
    2. Hemoglobin A1C on admission
  5. Protocol: Complete Insulin Orders
    1. Basal Insulin: Long acting Insulin (e.g. Lantus, NPH)
      1. Do not adjust Lantus for PO intake
      2. NPH may require adjustment if covering mealtime
    2. Bolus Insulin: Lispro, Aspart
      1. Cover meals, snacks with units per carbohydrate
    3. Hypoglycemia Management
    4. Hyperglycemia coverage: Sliding scale coverage
      1. Cover as units per glucose 50 mg/dl over 150 mg/dl
      2. Adjust per condition
        1. Lower doses
          1. Low weight Type I Diabetes Mellitus
          2. Renal Failure (Insulin 50% renal excreted)
        2. Higher dose
          1. Large Type II Diabetes Mellitus
          2. Corticosteroid use
          3. Sepsis or severe illness

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