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II. Management: Specific Antidotes for Analgesic overdoses

III. Management: Specific Antidotes for cardiovascular agent overdoses

IV. Management: Specific Antidotes for miscellaneous overdoses

  1. Anticholinergics
    1. Physostigmine
  2. Arsenic
    1. BAL chelation
    2. DMSA
  3. Carbon Monoxide
    1. Oxygen
  4. Cyanide
    1. Nitrites (Cyanokit, Sodium nitrite, Sodium thiosulfate)
    2. Hydroxycobalamin
    3. Oxygen
  5. Fluoride
    1. Calcium
  6. Hydrazines
    1. Pyridoxine
  7. Iron
    1. Deferoxamine (Desferal)
  8. Isoniazid (INH)
    1. Pyridoxine
  9. Lead
    1. BAL chelation
    2. DMSA
    3. Succimer
  10. Mercury
    1. Succimer
    2. DMSA
  11. Methanol or Ethylene Glycol
    1. Ethanol 10%
    2. Fomepizole (Antizol)
  12. Methemoglobinemia
    1. Methylene blue
  13. Organophosphates or Cholinergics
    1. Atropine
    2. 2-PAMCl
  14. Oxalates
    1. Calcium
  15. Sulfonylurea
    1. See Sulfonylurea Overdose
    2. Octreotide (Sandostatin)
    3. Dextrose
    4. Glucagon (temporizing measure only)
  16. Tricyclic Antidepressants overdose
    1. Sodium Bicarbonate to alkalinize the urine
    2. Benzodiazepines for Seizure (avoid other anticonvulsants)
  17. Warfarin
    1. Vitamin K
    2. Fresh Frozen Plasma

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