Emergency Medicine Book

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Neurogenic Shock

Aka: Neurogenic Shock
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  1. See Also
    1. Spinal Shock
    2. Hemorrhagic Shock
  2. Pathophysiology
    1. Results from severe Head Injury
    2. Peripheral sympathetic denervation (ungoverned parasympathetic activity)
  3. Signs
    1. Hypotension
      1. Secondary to Bradycardia and vasodilation
    2. Bradycardia
    3. Decreased vascular tone (vasodilation)
      1. Warm extremities
  4. Differential Diagnosis
    1. Hemorrhagic Shock (first priority to manage)
      1. Presents with Tachycardia, Vasoconstriction and cold extremities
      2. In actuality, distinguishing from Neurogenic Shock can be difficult
      3. Hemorrhagic Shock is more common, more immediately deadly and more treatable and should be addressed first
  5. Pitfalls
    1. Fluid Overload (from aggressive fluid Resuscitation)
  6. Management
    1. Careful fluid replacement
    2. Pressors (Norepinephrine is preferred)
    3. Target mean arterial pressure of 85 mmHg or higher (maximizes spinal cord perfusion)
  7. Prognosis
    1. Neurogenic Shock is a critcial Head Injury to the point of terminal event
    2. Prognosis is often poor

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