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Cholesteatoma
- Pathophysiology
- Benign squamous metaplasia of middle ear epithelium
- TM epithelium retracts into mastoid air cells
- Mass gradually expands and keratinizes
- Forms epithelial inclusion cyst
- Contains Cholesterol crystals and keratinous debris
- Results in destruction of middle ear ossicles
- Benign squamous metaplasia of middle ear epithelium
- Cause
- Congenital cholesteatoma
- Acquired cholesteatoma
- Symptoms
- Ear fullness
- Ear Pain
- Headache
- Hearing Loss
- Chronic suppurative discharge from middle ear
- Via perforated tympanic membrane
- Signs
- Middle ear deafness
- Otoscope Exam
- Pearly gray middle ear mass
- Radiology
- Bony Erosion and enlargement of middle ear
- Mastoid process with air cell opacification
- Management
- Surgical excision of cholesteatoma
- Second look procedure may be scheduled at 6 months
- Complications
- Conductive Hearing Loss
- Mastoiditis (most common cause)
Cholesteatoma (C0008373) | |
|---|---|
| Definition (MSH) | A non-neoplastic mass of keratin-producing squamous EPITHELIUM, frequently occurring in the MENINGES; bones of the skull, and most commonly in the MIDDLE EAR and MASTOID region. Cholesteatoma can be congenital or acquired. Cholesteatoma is not a tumor nor is it associated with high CHOLESTEROL. |
| Definition (CSP) | non-neoplastic keratinizing mass with stratified squamous epithelium, frequently occurring in the meninges, central nervous system, bones of the skull, and most commonly in the middle ear and mastoid region. |
| Concepts | Disease or Syndrome (T047) |
| ICD9 | 385.30 |
| English | Cholesteatoma, Cholesteatomas, Epidermoid cholesteatoma |
| Spanish | colesteatoma, colesteatoma epidermoide |
| Parent Concepts | Disorder of middle ear (C0271428), Keratosis (C0022593), Cholesteatoma of middle ear / mastoid (C0008374), Non-Neoplastic Head and Neck Disorder (C1335014), Ear Diseases (C0013447), Hyperkeratosis (C0870082) |
| Sources | AOD, COSTAR, CSP, ICD9CM, LCH, MSH, NCI, NDFRT, SCTSPA, SNOMEDCT Derived from the NIH UMLS (Unified Medical Language System) |
