Diffuse Hyperpigmentation

Aka: Diffuse Hyperpigmentation, Melanism, Diffuse Hypermelanosis, Melanosis

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II. Causes

  1. Excessive Melanin deposition: Addison's Disease
  2. Excessive Melanocytes: Phototoxic Drug Reaction

III. Signs

  1. Diffuse brown discoloration of skin
  2. Oral Mucosa pigmentation
  3. Accentuated areas
    1. Palmar creases
    2. Recent scars
    3. Pressure points at elbow, knee, and knuckles

IV. Differential Diagnosis

  1. Localized Lesions (increased Melanin or Melanocytes)
    1. See Brown Skin Lesion
    2. See Black Skin Lesion
  2. Diffuse skin changes
    1. See Skin Discoloration
    2. See Hyperpigmentation
    3. See Medication Causes of Hyperpigmentation

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Related Studies

Related Topics in Pigmentation Disorders

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