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Differin
Aka: Differin, Adapalene- Indication
- Mechanism
- Comedolytic
- Synthetic retinoid analog
- Supplied
- Gel 0.1%
- Adverse Effects
- Same as Tretinoin, but may be less severe
- Efficacy
- Reference
| Medication Costs | ||
|---|---|---|
| Differin (on 2/9/2012 at DrugStore.com) | ||
| Differin 0.1% Gel 45gm Tube | #1 for $308.85 | ($308.85/unit) |
| Differin 0.1% Cream 45gm Tube | #1 for $305.99 | ($305.99/unit) |
| Differin 0.3% Gel 45gm Tube | #1 for $255.98 | ($255.98/unit) |
| Adapalene (on 2/9/2012 at DrugStore.com) | ||
| Adapalene 0.1% Gel 45gm Tube | #1 for $159.99 | ($159.99/unit) |
| Adapalene 0.1% Cream 45gm Tube | #1 for $232.99 | ($232.99/unit) |
| FPNotebook does not benefit financially from showing this medication data or their pharmacy links. This information is provided only to help medical providers and their patients see relative costs. Insurance plans negotiate lower medication prices with suppliers. Prices shown here are out of pocket, non-negotiated rates. See Needy Meds for financial assistance information. | ||
adapalene (C0165631) |
|
|---|---|
| Definition (NCI) | A topical retinoid-like compound, chemically similar to vitamin A. Although the exact mechanism of action is unknown, adapalene binds to specific retinoic acid receptors in the nucleus, leading to specific gene expression. This agent stimulates skin growth through modulation of cellular differentiation, inflammatory processes and keratinization of follicular epithelial cells. Adapalene may increase dermal sensitivity to ultraviolet radiation. (NCI04) |
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | C063610 |
| SnomedCT | 332377001, 391719005, 108903004, 386934008 |
| English | 6-(3-(1-adamantyl)-4-methoxyphenyl)-2-naphthoic acid, adapalene, 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid, 6-(4-Methoxy-3-tricyclo(3.3.1.13,7)dec-1-ylphenyl)-2-naphthalenecarboxylic Acid, ADAPALENE, retinoids adapalene, adapalene (medication), Adapalene - chemical (substance), adapalene [Chemical/Ingredient], Adapalene, Adapalene (product), Adapalene (substance), Adapalene - chemical |
| Spanish | Adapalene - chemical, Adapalene, adapaleno (producto), adapaleno (sustancia), adapaleno |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |
Differin (C0593946) |
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|---|---|
| Concepts | Organic Chemical (T109) , Pharmacologic Substance (T121) |
| MSH | C063610 |
| English | Differin, differin, Allphar brand of adapalene, Differine, Galderma brand of adapalene |
| Sources |
Derived from the NIH UMLS (Unified Medical Language System) |