II. Indication

III. Preparations

  1. Clindamycin Gel, Lotion, Solution or foam 1%
  2. Clindamycin with Benzoyl Peroxide gel (Benzaclin): 1%/5% or 1.2%/2.5%
  3. Clindamycin with Tretinoin gel (Veltin, Ziana) 1.2%/0.025%

IV. Directions

  1. Apply a thin film qd/bid
  2. Often Used with a Comedolytic (Retin-A)

V. Advantages

  1. Only solution that reliably penetrates comedones
  2. Reaches bactericidal levels within comedones

VI. Disadvantages

  1. Resistance develops in 25% of patients within 6 months
    1. Use in combination with Benzoyl Peroxide (e.g. Benzaclin or seperate preparations)

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