II. Indication

III. Dosing

  1. Ointment applied qd-bid

IV. Efficacy

  1. Begin to see benefit in 2 weeks
  2. Maximum benefit in 6-8 weeks
    1. Resolution in 10% of patients
    2. Moderate Improvement in 70% of patients
    3. No Improvement in 20% of patients
  3. Useful adjunct to PUVA

V. Adverse effects

  1. May be irritating, more so in fold areas
  2. Do not use on face
  3. Vitamin D analog - risk of Hypercalcemia
    1. Limit to 100 grams per week

VI. Disadvantages

  1. Expensive ($100 for 2 ounces)

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Cost: Medications

calcipotriene (on 12/21/2022 at Medicaid.Gov Survey of pharmacy drug pricing)
CALCIPOTRIENE 0.005% CREAM Generic $1.02 per gram
CALCIPOTRIENE 0.005% OINTMENT Generic $2.14 per gram
CALCIPOTRIENE 0.005% SOLUTION Generic $0.97 per ml
CALCIPOTRIENE-BETAMETH DP OINT Generic $4.02 per gram
CALCIPOTRIENE-BETAMETHASONE DP 0.005%-0.064% SUSPENSION Generic $3.10 per gram