Dermatology Book

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Sebaceous Hyperplasia

Aka: Sebaceous Hyperplasia, Senile Hyperplasia, Senile Sebaceous Hyperplasia
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  1. Epidemiology
    1. Onset in middle age
    2. Rarely occurs at Puberty in familial forms
  2. Pathophysiology
    1. Composed of mature Sebaceous Glands with dilated duct
  3. Causes
    1. Most cases idiopathic with aging
    2. Cyclosporine
    3. Hemodialysis
  4. Signs
    1. Characteristics
      1. Yellow color
      2. Soft, dome-shaped Papules
      3. May be centrally umbilicated
      4. Usually 2-4 mm in size
    2. Distribution
      1. Forehead, Cheeks, Nose
      2. Vulva
  5. Differential Diagnosis
    1. Basal Cell Carcinoma
  6. Management
    1. Biopsy if suspect Basal Cell Carcinoma
    2. Cosmetic removal
      1. Electrodesiccation
      2. Laser
      3. Topical bichloracetic acid
      4. Avoid curettage due to scarring
      5. Multiple lesions have been treated with Accutane
  7. References
    1. Habif (1996) Dermatology, Mosby, p. 646-7
    2. Luba (2003) Am Fam Physician 64(3):729-38

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