Dermatology Book

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Postinflammatory Hyperpigmentation

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  1. Definition
    1. Hyperpigmentation response to inflammation on dark skin
  2. Causes: Common precipitating lesions
    1. Acne Vulgaris
    2. Psoriasis
    3. Atopic Dermatitis
    4. Contact Dermatitis
    5. Lichen Planus
  3. Signs
    1. Irregular, dark Macules and patches at sites of injury or inflammation
  4. Management
    1. General
      1. Most effective protocol is to use these agents in combination
      2. Example
        1. Hydroquinone 2% with Glycolic Acid 10% applied twice daily
        2. Tretinoin applied at bedtime
    2. Bleaching agents
      1. Hydroquinone (Eldoquin Forte) 2-4% applied twice daily
    3. Chemical peels
      1. Salicylic acid
      2. Glycolic Acid peel
    4. Keratolytics
      1. Azelaic Acid (Azelex) 20% cream applied twice daily
      2. Tretinoin (Retin-A) 0.025-0.050% applied at bedtime
      3. Tazarotene (Tazorac) 0.1% cream applied at bedtime
  5. Course
    1. Changes can persist for years
  6. References
    1. Burns (1997) Dermatol Surg 23(3):171

Postinflammatory hyperpigmentation (C0333616)

ConceptsPathologic Function (T046)
EnglishPost-inflammatory hypermelanosis, Post-inflammatory hyperpigmentation, Postinflammatory hyperpigmentation
Spanishhipermelanosis posinflamatoria, hiperpigmentacion posinflamatoria
Parent ConceptsHyperpigmentation (C0162834), Postinflammatory skin pigmentation change (C0521479), Degenerative disorder (C1285162), Duplicate concept (C1274013)
SourcesMTH, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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