Dermatology Book

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Wart Immune TherapyAka: Intralesional Candida Injection

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  1. See Also
    1. Cimetidine wart therapy
    2. Squaric Acid Wart Therapy
  2. Indication
    1. Common Warts refractory to other treatments
      1. Not FDA approved (anecdotal support only)
  3. Preparation
    1. Killed Candida (Monilia albicans)
    2. Used in Manitou control (1:1000 solution)
  4. Application
    1. Preparation
      1. Mix equal parts of 1% Xylocaine without Epinephrine
      2. Use 30 gauge needle
      3. Choose largest wart
    2. Injection
      1. Inject 0.1 cc to 0.3 cc intradermal beside wart
      2. Wart should blanche with injection
  5. Precautions
    1. Wear protective glasses
    2. Limit to 3 monthly injections
  6. Efficacy
    1. Limited literature regarding use
    2. Limited clinical experience
    3. Anecdotal efficacy: 80%
  7. Suppliers of Candida Antigen
    1. Greer Labs
    2. Allermed Labs (Candin)
      1. Standard use is for testing for DTH Response
      2. Address: P.O. 17540, San Diego, CA 92177-7540
      3. Phone: (858) 292-1060
      4. Cost: $76/1 ml vial (10 doses)
      5. Shelf life: 1 year
  8. References
    1. (1990) AAFP Clinical Perspectives
    2. (1999) Pfenninger, Hot Topics in Procedures
    3. Johnson (2001) Arch Dermatol 137:451

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