Dermatology Book

http://www.fpnotebook.com/

CiclopiroxAka: Loprox, Penlac

Advertisement

  1. See Also
    1. Topical Antifungal
  2. Indications
    1. Dermatophyte Infection (Tinea Corporis)
    2. Cutaneous Candidiasis
    3. Tinea Versicolor
  3. Preparations
    1. Cutaneous dermatophytes: Ciclopirox olamine 1% (Loprox)
    2. Onychomycosis: Ciclopirox 8% lacquer (Penlac)
  4. Mechanism: Broad-spectrum activity
    1. Antifungal for dermatophytes and yeast
    2. Some antibacterial activity in vitro
      1. Gram Positive Bacteria
      2. Gram Negative Bacteria
  5. Efficacy
    1. Tinea Pedis
      1. More effective than OTC Clotrimazole (Lotrimin)
    2. Onychomycosis (not recommended)
      1. Requires 48 week application
      2. Minimally better than Placebo for cure rates
      3. Partial clearance rates are also poor

ciclopirox (C0055711)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHC011585
Englishciclopirox, CICLOPIROX PREPARATION, cyclopirox
Spanishciclopirox
Parent ConceptsAntifungal Agents (C0003308), Pyridones (C0034260), [DE102] ANTIFUNGAL, TOPICAL (C0973520), Skin antifungal agent (C0304591), Mucous membrane antifungal agent (C0304592), Drug allergen (C1320237), Dermatological Antifungals (C1579274)
SourcesMSH, MTHSPL, NCI, NDFRT, RXNORM, SCTSPA, SNOMEDCT, USPMG, VANDF
Derived from the NIH UMLS (Unified Medical Language System)


Loprox (C0733447)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHC011585
EnglishLoprox
SourcesMSH, RXNORM
Derived from the NIH UMLS (Unified Medical Language System)


Penlac (C1130459)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHC011585
EnglishPenlac
SourcesMSH
Derived from the NIH UMLS (Unified Medical Language System)



Navigation Tree