Dermatology Book

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ButenafineAka: Mentax

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  1. See Also
    1. Topical Antifungal
    2. Tinea Infection
    3. Terbinafine
  2. Mechanism
    1. Naphthalenemethylamine derivative (similar to Terbinafine)
  3. Indications
    1. Refractory cutaneous Tinea Infections (e.g. Tinea Pedis, Tinea Cruris)
  4. Dosing
    1. Apply once daily for 14 days to a 2 cm area surrounding Skin Infection
    2. Note: Unlike other Topical Antifungals, once daily application is sufficient
  5. Advantages
    1. Shorter course (2 instead of 4 weeks) than Clotrimazole
    2. More convenient (once daily) than other Topical Antifungals
  6. Disadvantages
    1. Expensive
  7. Efficacy
    1. High tinea cure rates with a 2 week course
    2. At 4-8 weeks, no significant difference in cure as compared with Clotrimazole
  8. References
    1. Greer (1997) J Am Acad Dermatol 37(2 Pt 1):231
    2. Singal (2005) J Dermatolog Treat 16(5-6):331

butenafine (C0107497)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHC067594
Englishbutenafine, BUTENAFINE PREPARATION
Spanishbutenafina
Parent ConceptsBenzylamines (C0005106), Naphthalenes (C0027378), [DE102] ANTIFUNGAL, TOPICAL (C0973520), Antifungal Agents (C0003308), Naphthalenemethylamine derivative (C1689973), Dermatological Antifungals (C1579274)
SourcesMSH, NDFRT, RXNORM, SCTSPA, SNOMEDCT, USPMG, VANDF
Derived from the NIH UMLS (Unified Medical Language System)


Mentax (C0721666)

ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
MSHC067594
EnglishBertek brand of butenafine hydrochloride, Mentax
SourcesMSH, NCI, RXNORM
Derived from the NIH UMLS (Unified Medical Language System)



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