Dermatology Book

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Anthralin

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  1. Indication
    1. Psoriasis
  2. Dosing
    1. Use alone or in combination with UV light
    2. Should be used only by experienced practitioner
  3. Side Effects
    1. Irritation
    2. Stains clothing

Anthralin (C0003166)

Definition (MSH)An anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS.
Definition (NCI)A natural anthraquinone derivative, anti-psoriatic and anti-inflammatory Anthralin (dithranol) controls skin growth by reducing DNA synthesis and mitotic activity in the hyperplastic epidermis, restoring a normal rate of cell proliferation and keratinization. Used topically in the treatment of psoriasis, dermatoses, and alopecia areata, it is also used in biomedical research due to its effect on EGFR autophosphorylation. (NCI04)
ConceptsOrganic Chemical (T109) , Pharmacologic Substance (T121)
EnglishAnthralin, ANTHRALIN PREPARATION, Dihydroxyanthranol, DIHYDROXYANTHRONE 010809, Dithranol
Spanishantralina
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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