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MiliariaAka: Miliaria rubra, Prickly heat, Fox-Fordyce Disease, Miliaria alba, Miliaria sudamina, Apocrine miliaria, Miliaria crystallina, Miliaria Profunda, Heat rash, Lichen tropicus

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  1. See Also
    1. Newborn Skin Exam
  2. Pathophysiology
    1. Sweat retention when Eccrine Glands partially close
    2. Similar pathophysiology to Milia, but these 2 conditions are not the same
  3. Epidemiology
    1. Incidence: 40% of newborns
  4. Types: Common
    1. Miliaria crystallina (Miliaria alba, miliaria sudamina)
      1. Sweat infiltrates below Stratum Corneum
      2. Vessicles 1-2 mm without surrounding erythema on head, neck and trunk
        1. Noninflammatory Vesicles resemble water droplets
        2. Each vessicle ruptures and then desquamates and resolves within days
    2. Miliaria rubra (heat rash, default type of miliaria)
      1. Sweat infiltrates deeper, below Epidermis
        1. Inflammation associated with Sweat Gland obstruction
      2. Pruritic erythematous Papules and Vesicles on covered (over-heated) skin
  5. Types: Other
    1. Apocrine miliaria (Fox-Fordyce Disease)
    2. Miliaria profunda
      1. Limited to hot, humid climates
      2. Follows severe miliaria rubra
  6. Signs
    1. Papulovesicular lesions
    2. Distributed in intertriginous areas and occluded areas
  7. Differential Diagnosis
    1. See Neonatal Pustules and Vessicles
  8. Management
    1. Resolves spontaneously in first few months of life
    2. No treatment is needed
    3. Avoid occlusion and excessive heat
      1. Avoid over-dressing
      2. Consider cool baths (avoid prolonged exposure due to Hypothermia)
      3. Stay in cool air conditioned environments
  9. References
    1. Feng (1995) Cutis 55:213
    2. O'Connor (2008) Am Fam Physician 77:47

Fox Fordyce disease (C0016632)

Definition (MSH)Chronic pruritic disease, usually in women, characterized by small follicular papular eruptions in apocrine areas. It is caused by obstruction and rupture of intraepidermal apocrine ducts. (From Dorland, 27th ed)
ConceptsDisease or Syndrome (T047)
ICD9705.82
MSHD005588
EnglishApocrine miliaria, Chronic itching papular eruption of axillae and pubes, Chronic itching papular eruption of axillae AND/OR pubes, FOX FORDYCE DIS, Fox Fordyce Disease, Fox-Fordyce Disease
Spanishenfermedad de Fox - Fordyce, erupcion papulosa pruriginosa cronica de axila y pubis, erupcion papulosa pruriginosa cronica de axila Y/O pubis, miliaria apocrina
Parent ConceptsOther specified sweat gland disorders (C0157735), Miliaria (C0026113), Disorder of apocrine gland (C0406488), Duplicate concept (C1274013)
SourcesDXP, ICD9CM, MSH, MTH, NDFRT, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Miliaria (C0026113)

Definition (MSH)A syndrome of cutaneous changes associated with sweat retention and extravasation of sweat at different levels in the skin. Miliaria rubra, or prickly heat, results from apocrine duct obstruction. The sweat then seeps into the epidermis, producing pruritic erythematous papulovesicles. (From Dorland, 27th ed)
ConceptsDisease or Syndrome (T047)
MSHD008883
EnglishMiliaria
Spanishmiliaria
Parent ConceptsSweat Gland Diseases (C0038986), SKIN INFECTION/INFLAMMATION (C0549663), Syndrome (C0039082), Disease of Skin and Appendages (C0037272), skin disorder (C0037274), Duplicate concept (C1274013)
SourcesCOSTAR, CSP, CST, MSH, MTH, NCI, NDFRT, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Miliaria Rubra (C0162423)

ConceptsDisease or Syndrome (T047)
ICD9705.1, 705.1
MSHD008883
EnglishHeat rash, Miliaria crystallina, Miliaria Rubra, Miliaria tropicalis, Prickly Heat, Prickly heat - miliaria, Sudamina, Sweat rash
Spanishmiliaria cristalina, miliaria rubra, miliaria tropical, rash por calor, salpullido por calor, sarpullido por calor, sudamina
Parent ConceptsSweat Gland Diseases (C0038986), Miliaria (C0026113), Skin disorder due to physical agent AND/OR foreign substance (C0458392), Ambiguous concept (C1274012), Duplicate concept (C1274013)
SourcesCOSTAR, ICD9CM, MSH, MTH, MTHICD9, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Miliaria profunda (C0263468)

ConceptsDisease or Syndrome (T047)
EnglishMiliaria profunda
Spanishmiliaria profunda
Parent ConceptsMiliaria (C0026113), Duplicate concept (C1274013)
SourcesSCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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