Dermatology Book

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Hyperpigmentation in PregnancyAka: Chadwick's Sign, Linea Nigra

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  1. Physiology
    1. Melanocyte stimulating hormone rises in early pregnancy
    2. Increased Melanin deposition
  2. Signs: General
    1. Scarred areas and nevi darken
    2. Pigmented areas become more pigmented
      1. Areola
      2. Axilla
      3. External genitalia
      4. Anal region
      5. Linea nigra
  3. Signs: Specific
    1. Chadwick's Sign
      1. Darkened vulva and vagina
    2. Melasma or Chloasma (Mask of pregnancy)
      1. Dark areas under eyes and bridge nose
    3. Linea Nigra
      1. Dark midline low abdomen

Linea nigra (C0278057)

ConceptsFinding (T033)
EnglishLinea nigra, Pigmentation of linea alba of abdomen
Spanishlinea negra, linea nigra, pigmentacion de la linea alba del abdomen
Parent ConceptsClinical sign related to pregnancy (C0233179)
SourcesSCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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