Dermatology Book

Nail DiscolorationAka: Leukonychia, Red Nails, Blue Nails, Melanonychia, Chromonychia, Half-and-half nail, White Nails, Yellow Nails, Black Nails, Green Nails


  1. See Also
    1. Fingernail
    2. Nail Abnormality
    3. Transverse Linear Nail Lesion
    4. Nail Longitudinal Striation
    5. Nail Abnormality
  2. Definitions: Chromonychia
    1. Color changes of nails
  3. White Nail:Leukonychia (partial or complete)
    1. Congenital (autosomal dominant)
    2. Terry's Nails (all white nails)
    3. Half and Half Nails (white proximal, pink/red distal)
    4. Transverse Linear Nail Lesions
      1. Muehrcke's Lines
      2. Mees' Lines
      3. Transverse striate leukonychia (white lines)
        1. Minor nail matrix or Cuticle trauma
    5. Leukonychia punctata (white spots)
      1. Minor trauma to nail Cuticle or matrix
  4. Miscellaneous Color Changes
    1. Green Nails
      1. Pseudomonas pyocyanea infection
    2. Red Nails
      1. Nail Telangiectasia
      2. Congestive Heart Failure
  5. Blue Nails
    1. Medication Side Effect
      1. Quinacrine
      2. Chloroquine
      3. Minocycline (Minocin)
      4. Doxorubicin (Adriamycin)
      5. Melphalan, Bleomycin, Daunorubicin
    2. Wilson's Disease (Azure lunula)
    3. Ochronosis
    4. Psoriasis
    5. Alopecia Areata
    6. Silver Poisoning (Argyria)
  6. Black Nails (Melanonychia) or dark longitudinal streaks
    1. See Nail Abnormality for other longitudinal striations
    2. Medication Side Effects
      1. Cyclophosphamide (Cytoxan)
      2. Excessive Fluoride Supplementation (Fluorosis)
    3. Melanonychia striata
      1. Common in dark skinned persons
      2. Spontaneous or second to trauma or Chemotherapy
    4. Benign Nevus
      1. Uniform brown longitudinal streak localized to nail
    5. Subungual Melanoma
    6. Chronic Renal Failure
      1. Distal nail bed discolored brown
  7. Yellow Nails
    1. Yellow Nail Syndrome
    2. Onychomycosis
    3. Psoriasis
    4. Alopecia Areata
    5. Raynaud's Syndrome
    6. Hyperthyroidism
    7. Tetracycline
  8. References
    1. Fawcett (2004) Am Fam Physician 69(6):1417

Leukonychia (C0240182)

ConceptsDisease or Syndrome (T047)
EnglishLeuconychia, Leukonychia
Parent ConceptsNail Diseases (C0027339), Nail discoloration (C0221345)
Derived from the NIH UMLS (Unified Medical Language System)

Melanonychia (C1142305)

ConceptsFinding (T033)
Parent ConceptsDisorder of nail color (C1304385)
Derived from the NIH UMLS (Unified Medical Language System)

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