Dermatology Book

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SporotrichosisAka: Sporothrix schenckii

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  1. Pathophysiology
    1. Saprophytic, Dimorphic fungus
    2. Prototypal example of Nodular Lymphangitis
  2. Exposure risks
    1. Soil or plant debris
    2. Thorns
    3. Sphagnum moss
    4. Timber
    5. Animal Bites or scratches
  3. Signs
    1. Primary lesion after 1-12 week incubation
      1. Nodular lesion develops at site of inoculation
    2. Secondary lesions
      1. Erythematous Papules, Nodules develop up lymph chain
      2. Lesions ulcerate and drain clear serous fluid
    3. Other findings
      1. Rarely fever or regional adenopathy occur
  4. Differential Diagnosis
    1. See Nodular Lymphangitis
  5. Labs
    1. Routine fluid culture negative
    2. Culture of biopsied tissue shows saprophytic fungi
  6. Management
    1. Apply warm compresses for 40 to 60 minutes per day
    2. Antifungal for 2 months after lesion resolution
      1. Itraconazole 200 mg PO qd (preferred)
      2. Terbinafine (Lamisil) 250 mg PO bid
      3. SSKI 5 drops PO tid (titrated to 40-50 drops tid)
  7. References
    1. Kauffman (1995) Clin Infect Dis 21:981
    2. Tobin (2001) Am Fam Physician 63(2):326

Sporotrichosis (C0038034)

Definition (MSH)The commonest and least serious of the deep mycoses, characterized by nodular lesions of the cutaneous and subcutaneous tissues. It is caused by inhalation of contaminated dust or by infection of a wound.
ConceptsDisease or Syndrome (T047)
ICD9117.1
MSHD013174
EnglishBEURMANN DISEASE, Infection by Sporothrix schenkii, SCHENCK DISEASE, Sporotrichoses, Sporotrichosis
Spanishesporotricosis, infeccion por Sporothrix schenkii
Parent ConceptsOther mycosis NOS (C0343846), Dermatomycoses (C0011630), Sporotrichosis (C0038034), Infection by Deuteromycetes (C0276698)
SourcesCOSTAR, CSP, DXP, ICD9CM, LCH, MSH, MTH, NDFRT, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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