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MoleAka: Dermal Nevus, Junctional Nevus, Melanocytic Nevus, Nevocellular Nevus

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  1. See Also
    1. Congenital Melanocytic Nevus (C1318558)
    2. Atypical Nevus
    3. Melanoma
    4. Melanoma Risk Factors
  2. Epidemiology
    1. Onset after age 6-12 months and typically by age 20 years
    2. Common Incidence in Caucasian skin
      1. Typical Caucasian adults have 20 nevi
    3. Less common in pigmented skin (e.g. Black)
  3. Classification
    1. Junctional Melanocytic Nevus
      1. Cells at dermoepidermal junction
    2. Dermal Melanocytic Nevus
      1. Cells limited to Dermis
    3. Compound Melanocytic Nevus
      1. Combined features of Dermal and Junctional Nevi
  4. Signs
    1. General characteristics
      1. Small (< 1 cm)
      2. Sharply circumscribed
      3. Soft, round or oval Macules or dome shaped Papules
    2. Junctional Nevus Characteristics
      1. Minimally raised Papule or flat Macule
      2. Smooth regular borders
      3. Tan, brown or dark brown color
      4. Distribution
        1. Palms and soles
        2. Trunk
        3. Face
        4. Upper extremities
        5. Lower extremities
    3. Dermal Nevus
      1. Skin-colored, tan or brown colored Papules
      2. Round, dome-shaped, well circumscribed Papules
      3. Distribution
        1. Most common: Face and neck
        2. Other locations: Trunk, extremities
  5. Differential Diagnosis
    1. Junctional Nevus larger than 1 cm
      1. Congenital Nevus
      2. Dysplastic Nevus
    2. Dermal Nevus
      1. Basal Cell Carcinoma
      2. Dysplastic Nevus
  6. Management
    1. See Atypical Nevus

Melanocytic nevus (C0027962)

Definition (MSH)A nevus containing melanin. The term is usually restricted to nevocytic nevi (round or oval collections of melanin-containing nevus cells occurring at the dermoepidermal junction of the skin or in the dermis proper) or moles, but may be applied to other pigmented nevi. (From Dorland, 27th ed)
Definition (CSP)nevus containing melanin; usually restricted to nevocytic nevi (round or oval collections of melanin-containing nevus cells occurring at the dermoepidermal junction of the skin or in the dermis proper) or moles, but may be applied to other pigmented nevi.
Definition (NCI)A benign growth on the skin (usually tan, brown, or flesh-colored) that contains a cluster of melanocytes and surrounding supportive tissue.
Definition (NCI)(NEE-vus) A benign growth on the skin, such as a mole. A mole is a cluster of melanocytes and surrounding supportive tissue that usually appears as a tan, brown, or flesh-colored spot on the skin. The plural of nevus is nevi (NEE-vye).
Definition (NCI)Also known as mole, this is a neoplasm composed of melanocytes that usually appears as a dark spot on the skin. The plural of nevus is nevi (NEE-vye).
Definition (NCI)A nevus characterised by the presence of excessive pigment.
ConceptsNeoplastic Process (T191)
MSHD009508
EnglishMelanocytic naevus, Melanocytic naevus of skin, Melanocytic Nevi, Melanocytic nevus, Melanocytic nevus of skin, Melanotic Nevus, Mole, Mole of skin, Naevus, NERVUS PIGMENTED, Nevi, NEVI MELANOCYTIC, NEVI PIGMENTED, Nevus, NEVUS MELANOTIC, NEVUS PIGMENTATION, PIGMENTED MOLE, PIGMENTED MOLES, Pigmented naevus, Pigmented naevus of skin, Pigmented nevi, Pigmented nevus, Pigmented nevus of skin, Sutton's naevus, Sutton's nevus
Spanishnevo, nevo melanocitico, nevo melanocitico de piel, nevo pigmentado, nevus, nevus melanocitico, nevus melanocitico de piel
Parent ConceptsNevus (C0027960), Melanocytic nevus (C0027962), Melanocytic neoplasm (C1302746), Skin lesion (C0037284), Benign Neoplasm (C0086692), Mass of skin (C0281981), Ambiguous concept (C1274012), Acquired melanocytic nevus (C1302707), Neoplasm and/or hamartoma (C1302761), Duplicate concept (C1274013)
SourcesCOSTAR, CSP, CST, DXP, MSH, MTH, NCI, NDFRT, OMIM, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Nevus, Intradermal (C0206737)

Definition (MSH)A nevus in which nests of melanocytes are found in the dermis, but not at the epidermal-dermal junction. Benign pigmented nevi in adults are most commonly intradermal. (Stedman, 25th ed)
Definition (NCI)A nevus characterized by the proliferation of nevus cells in the dermis without involvement of the dermal-epidermal junction.
ConceptsNeoplastic Process (T191)
MSHD018330
EnglishCellular naevus, Cellular nevus, Dermal cellular naevus, Dermal cellular nevus, Dermal naevus, Dermal nevus, IDN - Intradermal naevus, IDN - Intradermal nevus, Intradermal melanocytic naevus, Intradermal melanocytic nevus, Intradermal naevus, Intradermal Nevi, Intradermal nevus
Spanishnevo celular dermico, nevo dermico, nevo intradermico
Parent ConceptsNevus (C0027960), Benign melanoma (C1456781), Benign neoplasm of skin (C0004998), Melanocytic nevus (C0027962), Melanocytic tumor of skin (C0349501), Acquired melanocytic nevus (C1302707)
SourcesCOSTAR, MSH, NCI, NDFRT, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)


Junctional nevus (C0334433)

Definition (NCI)(JUNK-shun-ul NEE-vus) A mole found in the junction (border) between the epidermis and dermis layers of the skin. These moles may be pigmented and slightly raised, and have a higher risk of developing into malignant melanoma.
Definition (NCI)A nevus characterized by the presence of an intraepidermal proliferation of nevus cells. The nevus cells form multiple nests in the dermal-epidermal junction. It presents as a small, slightly raised, pigmented skin lesion.
ConceptsNeoplastic Process (T191)
EnglishIntra-epidermal naevus of skin, Intra-epidermal nevus of skin, Intraepidermal naevus, Intraepidermal nevus, Intraepidermal Nevus of Skin, Intraepidermal Nevus of the Skin, Junction naevus, Junction nevus, Junctional melanocytic naevus, Junctional melanocytic naevus of skin, Junctional melanocytic nevus, Junctional melanocytic nevus of skin, Junctional melanocytoma, Junctional naevus, Junctional nevus, Junctional Nevus of Skin, Junctional Nevus of the Skin, Junctional Skin Nevus
Spanishmelanocitoma de la union dermoepidermica, nevo de la union, nevo de la union dermoepidermica, nevo intraepidermico, nevo intraepidermico de la piel, nevo melanocitico de la union dermoepidermica de la piel
Parent ConceptsBenign melanoma (C1456781), Benign neoplasm of skin (C0004998), Melanocytic nevus (C0027962), Melanocytic tumor of skin (C0349501), Acquired melanocytic nevus (C1302707)
SourcesNCI, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



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