Dermatology Book

http://www.fpnotebook.com/

Dysplastic NevusAka: Compound Nevus with Associated Architectural Disorder

Advertisement

  1. Spectrum of Nevus findings
    1. Compound Nevus
    2. Compound Nevus with associated architectural disorder
      1. Mild cytologic atypia
      2. Severe cytologic atypia
    3. Atypical melanocytic hyperplasia (Melanoma in-situ)
    4. Melanoma
  2. Definition of Dysplastic Nevi
    1. Entirely flat Nevi >5mm
    2. Variable pigmentation
    3. Irregular asymmetric outline
    4. Indistinct borders
  3. Correlation to Melanoma
    1. Small Nevi (2-5 mm)
      1. Under 25 small nevi: RR=1.0
      2. Over 100 small nevi: RR=3.1
    2. Larger Non-dysplastic nevi (>5 mm)
      1. Over 9 non-dysplastic nevi: RR=2.3
    3. Dysplastic nevi
      1. One dysplastic nevi: RR=2.2
      2. Over 9 dysplastic nevi: RR=12.0
  4. Reference
    1. Tucker (1997) JAMA 277:1439

Dysplastic Nevus (C0205748)

Definition (NCI)(dis-PLAS-tik NEE-vus) An atypical mole; a mole whose appearance is different from that of a common mole. A dysplastic nevus is generally larger than an ordinary mole and has irregular and indistinct borders. Its color frequently is not uniform and ranges from pink to dark brown; it is usually flat, but parts may be raised above the skin surface.
Definition (NCI)(dis-PLAS-tik NEE-vye) Atypical moles; moles whose appearance is different from that of common moles. Dysplastic nevi are generally larger than ordinary moles and have irregular and indistinct borders. Their color frequently is not uniform and ranges from pink to dark brown; they usually are flat, but parts may be raised above the skin surface.
Definition (NCI)Solitary or multiple, slightly raised, pigmented lesions with irregular borders, usually measuring more than 0.6cm in greatest dimension. Morphologically, there is melanocytic atypia and the differential diagnosis from melanoma may be difficult. Patients are at an increased risk for the development of melanoma.
ConceptsNeoplastic Process (T191)
MSHD004416
EnglishAtypical naevus, Atypical naevus of skin, Atypical nevus, Atypical nevus of skin, Clark's Nevus, DN - Dysplastic naevus, DN - Dysplastic nevus, Dysplastic naevus, Dysplastic naevus of skin, Dysplastic Nevi, Dysplastic Nevus, Dysplastic nevus of skin, Lentiginous Nevus, NAD, Nevus with Architectural Disorder and Cytologic Atypia of Melanocytes
Spanishnevo atipico, nevo cutaneo atipico, nevo cutaneo displasico, nevo displasico
Parent ConceptsMelanocytic nevus (C0027962), Melanocytic tumor of skin (C0349501), Cutaneous Precancerous Condition (C0877510), Benign neoplasm of skin (C0004998), Acquired melanocytic nevus (C1302707), Duplicate concept (C1274013)
SourcesMSH, MTH, NCI, SCTSPA, SNOMEDCT
Derived from the NIH UMLS (Unified Medical Language System)



Navigation Tree