Dermatology Book

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Sebaceous GlandAka: Sebum, Holocrine Secretion

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  1. Physiology
    1. Associated with Hair Follicles in hair covered areas
    2. Independent of Hair Follicles at mucosal margins
      1. Lips
      2. Eyelids
      3. Penis
      4. Labia Minora
      5. Nipples
    3. Secretes oily substance (sebum) onto hair
    4. Sebum acts to waterproof hair and skin
  2. Histology
    1. Acinus produces sebum
      1. Round cells with lipid-filled vacuoles
      2. Secretion of sebum known as holocrine secretion
    2. Branched acini join at short duct
    3. Duct empties into Hair Follicle
  3. Sebaceous Gland Conditions
    1. Epidermal Cyst
  4. References
    1. Wheater (1987) Functional Histology, p. 130-2
    2. Murphy in Cotran (1989) Robbins Pathology, p. 1277-8

Sebum (C0036511)

Definition (MSH)The oily substance secreted by SEBACEOUS GLANDS. It is composed of KERATIN, fat, and cellular debris.
Definition (NCI)(SEE-bum) An oily substance produced by certain glands in the skin.
ConceptsBody Substance (T031)
MSHD012629
EnglishSebum, Sebums
Spanishsebo, secrecion sebacea
Parent ConceptsSebaceous Glands (C0036505), Bodily secretions (C0036537), Skin Fluid or Secretion (C1519349), Body Fluids and Substances (C1521806), Body Fluids (C0005889), Body secretion (C0225351), Right external ear structure (C0229301), Left external ear structure (C0229302)
SourcesAOD, CSP, LCH, MSH, MTH, NCI, SCTSPA, SNOMEDCT, UWDA
Derived from the NIH UMLS (Unified Medical Language System)



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