Dermatology Book

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Nikolsky's Sign

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  1. Indication
    1. Evaluation of Bulla (Blister)
  2. Technique
    1. Lateral pressure applied to edge of bulla
    2. Positive test if bulla extends laterally with pressure
      1. Suggests Epidermis detaches from skin
  3. Causes of positive test
    1. Pemphigus Vulgaris

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