Cardiovascular Medicine Book

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HypertensionAka: Htn, Essential Hypertension

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  1. See Also
    1. Hypertension in Children
    2. Hypertension in Infants
    3. Hypertension in Pregnancy
    4. Hypertension in Athletes
    5. Hypertension in the Elderly
  2. Epidemiology
    1. Demographics
      1. White Adults in US: 20% are hypertensive
      2. Black Adults in US: 30% are hypertensive
      3. Of all hypertensives, >50% are over age 65 years
    2. Outcomes
      1. Best predictor to outcome varies by age
        1. Diastolic Blood Pressure best predictor <50 years
        2. SBP and DBP predict outcomes equally ages 50-59
        3. Pulse Pressure best predictor age >60 years
      2. Coronary Artery Disease
        1. Hypertension Causes 35-45% morbidity and mortality
      3. Cerebrovascular Accident
        1. Relative Risk increases 1.84 for each 10 mmHg DBP
        2. Midlife Hypertension raises longterm CVA risk
        3. Seshadri (2001) Arch Intern Med 161:2343
      4. Alzheimer's Disease
        1. Increased SBP in middle age is predisposing factor
      5. Reference
        1. (1995) Lancet 346(8991):1647
        2. Kivipelto (2001) BMJ 322:1447
  3. Hypertension Definition
    1. See Hypertension Criteria
  4. Types
    1. Essential Hypertension (Primary Hypertension)
      1. Stage 1-2 (DBP 90-104) in 80% of cases
    2. Accelerated Malignant Hypertension
      1. Recent substantial Blood Pressure increase
      2. Associated with retinal vessel damage
        1. Retinal Hemorrhages
        2. Retinal exudates
        3. Papilledema
      3. Diastolic Blood Pressure over 140
    3. Isolated Systolic Hypertension
      1. Systolic Blood Pressure: >160 mmHg
      2. Diastolic Blood Pressure: <90 mmHg
      3. Risks
        1. Coronary Artery Disease
        2. Cerebrovascular Accident
      4. Onset: 5th decade
      5. Affects 11% of those over age 75 years
      6. Results from progressive fall in vessel compliance
  5. Causes of secondary Hypertension
    1. See Hypertension Causes
  6. Diagnosis
    1. See Hypertension Criteria
  7. Hypertension Evaluation
    1. Hypertension Evaluation History
    2. Hypertension Evaluation Exam
    3. Hypertension Evaluation Labs
  8. Management
    1. See Hypertension Management

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