Cardiovascular Medicine Book

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Asystole

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  1. See Also
    1. Ventricular Fibrillation
    2. Pulseless Ventricular Tachycardia
    3. Guidelines 2000 CPR and Emergency Cardiovascular Care
  2. Causes
    1. Hypoxia
    2. Hypothermia
    3. Hyperkalemia
    4. Hypokalemia
    5. Preexisting acidosis
    6. Drug Overdose
  3. Pediatric Management
    1. Continue CPR
    2. Endotracheal Intubation immediately
    3. Obtain IV Access
    4. Confirm Asystole in more than one lead
    5. Consider Asystole causes as above
    6. Hyperventilate with 100% oxygen
    7. Epinephrine q3-5 minutes
      1. First Dose
        1. 0.01 mg/kg IV/IO (0.1 ml/kg of 1:10,000)
        2. 0.1 mg/kg ET (0.1 ml/kg of 1:1000)
      2. Subsequent doses
        1. 0.1 mg/kg IV/IO/ET (0.1 ml/kg of 1:1000)
    8. Consider Transcutaneous Pacing
      1. Use pediatric electrodes if less than 15 kg
  4. Adult Management
    1. Continue CPR
    2. Endotracheal Intubation immediately
    3. Obtain IV Access
    4. Confirm Asystole in more than one lead
    5. Consider Asystole causes as above
    6. Consider immediate Transcutaneous Pacing
    7. Epinephrine 1 mg IV push q3-5 minutes
      1. Consider Vasopressin as alternative
        1. Dose 40 Units IV for single, one time dose
        2. Considered superior to Epinephrine in Asystole
        3. Zepf (2003) N Engl J Med 350:105
    8. Atropine 1 mg IV q3-5 minutes to max total 0.04 mg/kg
    9. Consider termination of efforts
      1. Asystole refractory to above measures
      2. No reversible causes identified

Cardiac Arrest (C0018790)

Definition (MSH)Cessation of heart beat or MYOCARDIAL CONTRACTION. If it is treated within a few minutes, heart arrest can be reversed in most cases to normal cardiac rhythm and effective circulation.
Definition (CSP)cessation of the heart beat.
Definition (NCI)Cardiac standstill or arrest; absence of a heartbeat.
Definition (NCI)Sudden cessation of the pumping function of the heart, with disappearance of arterial blood pressure, connoting either ventricular fibrillation or ventricular standstill.
Definition (NCI)Sudden cessation of the pumping function of the heart, with disappearance of arterial blood pressure, connoting either ventricular fibrillation or ventricular standstill.
ConceptsPathologic Function (T046)
ICD9427.5
EnglishARREST CARDIAC, Asystole, Asystoles, Cardiac Arrest, CARDIAC ASYSTOLE, Cardiac standstill, Heart Arrest, STANDSTILL CARDIAC, VENTRICULAR ASYSTOLIA
Spanishasístole, asistole, asistolia, paro cardíaco, paro cardiaco
CreditsDerived from the NIH UMLS (Unified Medical Language System)



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